Papaverine ezibhebheni. Umthamo wamakati yi-1-2 mg nge-1 kg yesisindo sesilwane, emlonyeni izikhathi ezi-2 ngosuku.

I-Papaverine kuma-ampoules womjovo. Umthamo wamakati yi-1-2 mg nge-1 kg yesisindo sesilwane, ngokunqenqemeni / nge-intramuscularly izikhathi ezi-2 ngosuku.

I-Papaverine rectal suppository. Ukudonswa kwamakati ngo-1-2 mg nge-1 kg yesisindo sesilwane, ku-rectum, izikhathi ezi-2 ngosuku

Umthamo wezinja

Papaverine ezibhebheni. Umthamo wezinja ngu-1-3 mg nge-1 kg yesisindo sesilwane, emlonyeni izikhathi ezi-2 ngosuku.

I-Papaverine kuma-ampoules womjovo. Umthamo wezinja ungama-1-3 mg nge-1 kg yesisindo sesilwane, ngokunqenqemeni / nge-intramuscularly izikhathi ezi-2 ngosuku.

I-Papaverine rectal suppository. Ukudonswa izinja 1-2 mg nge 1 kg yesisindo sesilwane, kwi-rectum, izikhathi ezi-2 ngosuku

Incazelo ejwayelekile

I-antispasmodic ikhiqizwa ngamafomu amaningi omthamo:

• Ukungena. Uketshezi olungafihli lutho lugcwele kuma-ampoule angilazi abekwe uphawu. Abanye abakhiqizi basebenzisa amabhodlela ane-cap cap. Zibhekwa njengezilungele ukusetshenziswa, ngoba azikho izingozi zokulimala ngengilazi lapho zivulwa. I-1 ml yesisombululo imvamisa iqukethe u-20 mg we-papaverine hydrochloride. Ukwakheka kuhlanganisa namanzi ahlanziwe nezinye izinto.
• Amacwecwe. Amathebulethi amhlophe ayindilinga agcwele amaseli e-contour zezingcezu eziyi-10. Amakhemisi angena ngemithamo emibili - ithebhulethi eyodwa noma eyi-10 ingaqukatha u-10 noma 40 mg wento esebenzayo. Ngaphezu kwalokho, ukwakheka kufaka isitashi samazambane, i-talc, i-acid enukayo nezinye izinto ezenza umsebenzi wokusiza wodwa.
• Amakhandlela aqondisayo. Amakhandlela amancane osayizi agcwele amapuleti e-PVC. Ukuqoqwa kwento esebenzayo kubo yi-20 mg. Abagcotshwa banamafutha aqinile, i-emulsifier ne-stearin yezimonyo.

Emakati, i-Papaverine isetshenziswa kakhulu emjovo. Isixazululo sinesenzo esisheshayo, kepha amaphilisi awaphansi ekusebenzeni kahle. Umuthi osebenzayo ekwakhekeni kwawo, "usebenza" emzimbeni kuphela uhhafu (i-bioavailability - ama-54% kuphela). Amakhandlela ezilwane asetshenziswa ezimweni ezingandile.

Isebenza kanjani

Umuthi unomphumela we-antispasmodic, okungukuthi, amandla okuqeda ama-spasms. Futhi, umuthi udambisa izinhlungu ezihambisana nama-spasms, wehlise nomfutho wegazi. Umphumela wesidakamizwa kungenxa yokuthi into esebenzayo ivimba ukwakheka kwama-enzymes, ngenxa yalokho ithoni yezicubu ezibushelelezi ezakha isisu, isinye, izinso nezinye izitho zangaphakathi kuncishisiwe.

Lapho ithoni yemisipha ebushelelezi ikhuphuka kakhulu, kwenzeka i-spasm, evame ukuhambisana nobuhlungu obukhulu. Ngaphansi kwesenzo sikaPapaverine, izicubu zezitho zangaphakathi ziphumula, ithoni liyancipha. Futhi, umuthi usiza ukwandisa imithambo yegazi, ngenxa yokuthi umphumela we-hypotensive nawo utholakala (wehlisa umfutho wegazi). Futhi, umuthi unomphumela wokuthoba ohlelweni lwezinzwa oluphakathi. Kulokhu, uma usebenzisa i-Papaverine, izilwane ziba nokuthula, yeka ukukhombisa ukukhathazeka.

Qaphela! Umuthi uyakwazi ukuthinta ukusebenza kwenhliziyo, ngakho-ke kwenqatshelwe ngokuphelele ukusisebenzisa ezifuyweni ngaphandle kodokotela wezilwane.

Lapho eqokwa

Imiyalo yokusebenzisa umuthi ibhalelwe abantu, kepha uPapaverine usetshenziselwa amakati anezinkinga ezifanayo. Imvamisa kuyabekwa:

• ne-colic yamathumbu ebangelwa izifo kanye nezinye izinto,
• ngama-pathologies wesistimu yokugaya ukudla, ehambisana nobuhlungu obukhulu,
• ngezifo ezithathelwanayo zohlelo lwezitho zofuzo,
• nge-cystitis ebangelwa yi-hypothermia, amagciwane we-pathogenic nezinye izinto,
• nge-pylorospasm,
• nge-cholecystitis,
• nge-bronchospasm, njll.

Futhi, umuthi uvame ukusetshenziselwa amakati namakati ane-urolithiasis nokugcinwa komchamo okubangelwa ezinye izinto. Nikeza isidakamizwa ukuze ususe i-cramping, pain nezinye izimpawu ezifanayo. Isibonelo, nge-urolithiasis noma i-cystitis, uPapaverine ufakwa emakati ukuze kuqedwe ukugcinwa komchamo. Ngaphansi kwethonya lomuthi, i-bladder kanye ne-ducts iyaphumula, ngakho-ke isilwane siqala ukuzimela siye endlini encane.

Ezimweni eziningi, i-antispasmodic ihlanganiswa nezinye izidakamizwa, isenzo sayo okuhloswe ngaso ukuqeda imbangela ye-pathology, hhayi izimpawu. Khetha ukwelashwa okuxubayo kufanele kube udokotela wezilwane.

Qaphela! I-Papaverine inezinto eziningi eziphikisana futhi ingadala imiphumela emibi uma isetshenziswe ngendlela engafanele. Kulokhu, ukusetshenziswa kwayo ezilwaneni kuvunyelwe njengoba kuyalelwe udokotela.

Izindleko

Abanye abantu bakhetha i-papaverine yokwelapha amakati ngenxa yentengo yayo. Izindleko ze-ampoule eyodwa nge-2 ml ziqala kusuka kuma-ruble ayi-5, kanye nokufakwa kwamacwecwe kusuka kuma-ruble ayi-15. Umuthi uyatholakala kuwo wonke amakhemisi esintu, ngakho-ke, ubunzima bosesho bawo lapho uthenga ungakaze uvele.

Ungabona inani lamanje lesidakamizwa bese usithenga lapha:

Isetshenziswa kanjani

Umthamo wesidakamizwa ubalwa ngokuya ngesisindo sesilwane. Kungakhathalekile ukuthi kusetshenziswa amaphilisi noma imijovo, kukhilogremu ngayinye yesisindo sesilwane, i-1-2 mg yento esebenzayo iyadingeka, kepha udokotela kufanele abale umthamo oqondile, kucatshangelwa ubunzima besifo nezinye izici. Umuthi uphuzwa izikhathi ezi-1-2 ngosuku. Isikhathi sokwelashwa sinqunywa udokotela ngokuya ngesimo sempilo ejwayelekile, izici zenkambo yesifo, njll.

Kubalulekile! Inkambo yokusetshenziswa kwe-antispasmodic akufanele yedlule izinsuku eziyi-7. Ezimweni ezivame kakhulu futhi ngaphansi kokuqashwa ngudokotela ngokuqinile ukusetshenziswa okuvumelekile.

Imijovo

I-Papaverine ijwayele ukujovwa emakati emakatini. Ukuze wenze lokhu, donsela isibaya sesikhumba lapho ibuna, usihlabe ngenalithi oyinyumba ku-syringe futhi ungangeni ngokushesha emthini. Ukujova akunzima ukukwenza, ngakho abanikazi bezilwane eziningi bayakwenza. Ngomjovo, kungcono ukusebenzisa isirinji le-insulin. Ifakwe ngenalithi encane, ezokwenza kube lula ukubhoboza isikhumba esiminyene lapho kubuna ikati.

Ukuphathwa kwe-intramuscular of the drug nako kuvunyelwe. Ngale ndlela, imijovo ingaba buhlungu, ngoba ukungaphatheki kahle kwenzeka lapho inaliti noma isixazululo singena ku-nerve fiber. Uma kungekho makhono afanele, inkinga efanayo ivamile.

Amaphilisi namakhandlela

Izibhebhe zingafihlwa kokuphakelayo, kepha zinambitha ebabayo, ngakho amakati zivame ukuzikhipha. Kulokhu, kungcono ukunikeza umuthi ngenkani. Kulokhu, amaphilisi kufanele abekwe ezimpandeni zolimi, agcine ikhanda lesifuyo liphakanyiswa. Imvamisa umuthi okule fomu unikezwa ekuseni nakusihlwa.

Amakhandlela afakwa ku-anus ngokuya ngemiyalo esetshenzisiwe, kepha leli fomu lemithamo yezilwane liyivelakancane kakhulu.

Contraindication

Amathebulethi e-Papaverine nezinye izindlela zomthamo azikwazi ukusetshenziselwa ukwelapha amakati kulezi zimo ezilandelayo:

• nge-glaucoma
• ngokwehluleka kwesibindi,
• ukwephula izindlala ze-adrenal,
• uma kwenzeka uthukile,
• ngaphansi kwengcindezi enkulu
• nokulimala kobuchopho
• ngokwehluleka kwezinso.

Ngokuqapha, udinga ukusebenzisa umuthi we-tachycardia noma ezinye izinkinga zenhliziyo, kanye nomfutho wegazi ophansi. Kulokhu, lesi silwane kufanele sibe ngaphansi kokuqashwa udokotela wezilwane kukho konke ukwelashwa. Umuthi ubuye uhlukaniswe futhi uma kwenzeka kungabekezelelwa umuntu ngamunye.

Kubalulekile! Awukwazi ukuwusebenzisa umuthi wezikhumba zezinja + kuze kube izinyanga eziyisithupha ubudala.

Imiphumela emibi engaba khona

I-antispasmodic ingadala imiphumela elandelayo emakati emakati:

• isicanucanu nokuhlanza (kusetshenziswa amaphilisi, ukwanda kwe-salivery),
• ukozela kanye nokubola,
• umjuluko osindayo
• kwehlisa umfutho wegazi
• ukuphazamiseka kwesigqi senhliziyo
• ukuqunjelwa.

Njengoba umuthi usebenza ohlelweni oluphambili lwezinzwa, ukulahleka kwesikhashana kokuzwa noma ukubona, ukwehla kokuxwaya ukunakwa kungenzeka. Ingozi yemiphumela emibi iyanda lapho umthamo wedlulile, ngakho-ke, ukubonana nodokotela ngaphambi kokusetshenziswa kuyimpoqo.

Ukubuyekezwa komnikazi

Nina, unkosikazi wekati oneminyaka emithathu ubudala:

“Lapho ikati lethu uTimothy likhula, kwadingeka ukuthi akhishwe inyamazane, njengoba kuhlala amanye amakati amabili endlini. Ngemuva kwesikhashana, kwatholakala ukuthi une-urolithiasis, welashwa, ngempumelelo. Ngemuva kwezinyanga ezimbalwa, kwenzeka ukuthi kuhlaselwe - ikati alikwazanga ukuya endlini yangasese, futhi lapho kwenzeka, umchamo wawunegazi. Bekumele ngibuye emtholampilo futhi. Udokotela wanquma i-papaverine neminye imithi. Ezinsukwini ezimbalwa, ikati laba ngcono kakhulu. Manje izinkinga zokuchama zedlule. ”

UDmitry, umnikazi wekati lasePheresiya:

"Ikati lami aliphumi ngaphandle, inani lingahamba ngezinyawo ngewindows. Ngaphandle kwalokhu, endaweni ethile kwabanjwa i-cystitis. Ngibonile ukuthi uhlala esitokisini isikhathi eside, futhi kuphuma amaconsi ambalwa. Isikhathi sokuqala lapho umchamo ususwa kusetshenziswa i-catheter, kwabe sekufakwa umjovo uPatverine. Ikati lizwa ngcono, laqala ukuzichamela lodwa. Umuthi ushibhile futhi uyasebenza. "

Ukubuyekezwa kwezilwane

U-Elena, udokotela wezilwane ovela emtholampilo "Avet":

“I-Papaverine ingumuthi owenzelwe yonke indawo okufanele ube kwikhabethe lomuthi kuyo yonke imizi. Ilungele kahle abantu nezilwane. Imvamisa, ngibeka izinkinga zokuchama, yize kwesinye isikhathi kusiza ukususa izimpawu ze-pancreatitis nezinye izinkinga zesistimu yokugaya ukudla. ”

U-Andrey, udokotela wezilwane oneminyaka eyi-12 yesipiliyoni:

“UPapaverine, yize eyisidakamizwa somuntu, uvame ukusetshenziswa kwezokwelapha. Akubizi, kodwa kuyasebenza kakhulu, yize kungakufanele ukusebenzisa ngaphandle komyalelo kadokotela. Ukusetshenziswa ngokungafanele kungasizakali, kepha kukhulisa isimo sesilwane esigulayo. ”

Inhloso yesidakamizwa

IPapaverine isetshenziswa emakati ukuqabula ungqimba obushelelezi bemisipha yezindonga zezitho eziyize (isigaxa sezindlala nezinye) nezicubu zomzimba (ama-ureters, urethra nokunye okunjalo), okunomthelela ekwandeni kwazo. Imicu yemisipha ethambile nayo iyatholakala emithanjeni yoboya efana nama-artery kanye nama-arterioles, nawo aqabula ngaphansi kwesenzo se-papaverine. Kulesi simo, kukhona ukwehla kwesikhala kanye nobuhlungu esitho, kanye nokwenza ngcono ekuhlinzekweni kwegazi laso. Ngakho-ke, i-papaverine iyasebenza ezifweni zamakati ezinjenge-cholecystitis, cholangitis, urolithiasis, papillitis, cholecystolithiasis nezinye izimo ezifanayo ze-pathological.

Imiyalo yokusebenzisa

IPapaverine yamakati iyatholakala ngesimo sesisombululo somjovo, ifomu lethebhulethi, nangendlela yama-rectal suppositories. Umthamo ojwayelekile ngu-1-2 mg wento esebenzayo ngekhilogremu yesisindo somzimba wesilwane. Ikati kufanele lithole lo muthi womuthi kabili ngosuku. Imijovo yenziwa kahle ngokunqophela lapho kubuna ikati.

Kubalulekile! Nquma umuthi kufanele ube udokotela wezokwelapha kuphela. Ukuzilawula kwalo muthi, kanye noshintsho olungagunyaziwe umthamo kungaholela emiphumeleni emibi engathandeki kakhulu noma umphumela obulalayo wesilwane.

Izindlela zokuqapha

I-Papaverine ibhekana nobuhlungu kanye ne-spasm yemisipha ebushelelezi emakati, kepha isidakamizwa esiyingozi kakhulu. Uma kwenzeka kuba ne-overdose, izimo eziyingozi zingaqhamuka hhayi impilo yezilwane zasekhaya kuphela, kepha futhi nempilo yakhe. Izimo ezinjalo i-arrhythmia yenhliziyo nokuvinjwa okuhlukahlukene kwezixhaxu ze-conduction zenhliziyo. Ngakho-ke, lesi sidakamizwa sisetshenziswa kuphela ngemuva kokukhetha umthamo ngamunye ngudokotela wezokwelapha wezilwane wekati ngalinye nekati.

Okuqhamuka uma udla imishanguzo

• Ukuphazamiseka kwesigqi senhliziyo (arrhythmias),
• Ukwephulwa kwesigqi (blockade),
• Isicanucanu, ukuhlanza,
• Ukuphazamiseka kwesikhashana kwe-CNS (kwezokwelapha, wezokwelapha, amacala ayaziwa lapho amakati angalahlekelwa ukuzwa noma Amehlo awo amahora amaningi ngemuva kokujova i-papaverine. Izimo ezinjengalezi zenzeka ezigulini ezinamakhaza ezinokwehluleka kwezinso),
• Isici sokwelapha ukuqunjelwa kwe-papaverine,
• Abanikazi bayazi ukuthi ikati liba sibi futhi lilala cishe ngaso sonke isikhathi.

Kubalulekile! Uma kwenzeka kuvela ikati, yeka ukusebenzisa umuthi ngokushesha bese uthintana nodokotela wezilwane.

Ukubuyekezwa mayelana ne-papaverine

Lily:
“UTimosha wami waqala ukuba nenkinga yokuchama ngemuva kokuxoshwa. Akakwazanga ukuya endlini yangasese izinsuku eziningana. Kwabonakala ukuthi lwaphela kanjani phambi kwamehlo ethu. Walimala. Saya e-vet. Satshelwa ukuthi kwakudingeka ukugxekwa, ukuthi bekungeke kube nomqondo kusuka ekati.

Hhayi-ke, ungalalisa kanjani ikati lakho othandekayo? Nginqume ukuya komunye udokotela wezilwane ngilalele umbono wakhe. Usinikeze upapaverine ukuthi siyogwaza lapho libuna isonto lonke. Ngamangala ukuthi umuthi awubizi futhi uyasebenza! Ngemuva komjovo wokuqala, uTimosha waphila phambi kwamehlo ethu! Waya endlini encane, wadla, waqala ukuhambahamba ngasendlini! Injabulo yami ibingazi mngcele! Futhi manje impilo yami enhle iphila ngenjabulo. Kwesinye isikhathi kuvela amacala afanayo (kuyabuya, kubonakala sengathi), kepha inqubo ye-papaverine ihlala isisiza! ”

Ungenacala.
“Ikati lami lithwale inhlekelele efana ne-pancreatitis eqeda ukugula (isifo sokuvuvukala sanyikwe). Ikati lalihlushwa, lilinganiswa. Kuyaqondakala, ukuzamazama okunjalo emzimbeni. Ngokushesha ngaya naye kochwepheshe. Unikeze ukwelashwa, okubandakanya ukudambisa i-papaverine yezinhlungu nge-baralgin. Udokotela wezilwane ungixwayise ngokuthi i-papaverine ingadala imiphumela emibi futhi yangicela ukuthi ngihlale kudokotela wezilwane okungenani ihora ukwenza isiqiniseko sokuthi ikati liyakubekezelela umjovo.

Wayesemkhahlela lapho ebuna. UVader (ikati lami) akazange awuthande umjovo, kodwa ngemuva kwesikhashana wakhululwa. Ngakuzwa lokhu lapho ngihlala naye emtholampilo. Wasiphumuza isisu! Udokotela wasibheka, wathi manje usungayijova ngokuphepha ikhambi elinqunyelwe isonto bese ulungiselela ukuqokwa. Ngakho-ke phakathi nokwelashwa, uVader waze walala, waphumula. Ngenxa yalokho, ngibonga udokotela ne-papaverine nge-baralgin, ubuso obomvu obungenangqondo bugobhoza endlini yami! "

UMarianne.
“Ikati lami lalinesifo sezinso. Ngifunde kwenye indawo ukuthi nge-renal colic, eyenzeka nge-urolithiasis, abaniki i-shpa. Ngagibela kwi-Intanethi. Kufundwe kumaforamu ukuthi i-no-shpa (i-drotaverine ngolimi lwezokwelapha) imvamisa idala izinkinga zamakati nasemakati ukuyeka ukuhamba. Esikhundleni salokho, babhala ukuthi basebenzisa i-papaverine. Umuthi uyafakelwa lapho ubuna. Nginqume ukuzama ukuphamba kitty yami.

Ngenxa yalokho, yahamba igwebu emlonyeni, yayingakwazi ukuphefumula ngokujwayelekile! Ngayala itekisi ngishaqekile futhi ngashayela emtholampilo we-vet. Ngathukwa kakhulu lapho ngokuqala ukuzindla. Ngokusobala, angifundanga ngemiphumela emibi. Bengifuna ukonga odokotela. Ngenxa yalokhu, ngikhokha ngaphezulu okwamanje. Ngakho-ke mhlawumbe i-papaverine ingumuthi omuhle, kepha akufanele ungene ekusetshenzisweni kwayo ngaphandle kodokotela. Kungcono ukukhokhela udokotela wezilwane ukuze ahlole isimo sezilwane ezifuywayo. "

U-Ivan Alekseevich, udokotela wezokwelapha wezilwane:
“Sekuphele iminyaka eyi-15 ngisebenza emtholampilo. Ngokuvamile amakati alethwa kithi ngokuhlaselwa i-renal colic uma kwenzeka kwenzeka i-urolithiasis, eyakhula ngemuva kokuhlinzwa. Ngeshwa, lokhu akuyona into engjwayelekile. Futhi kaningi sizama ukufaka imijovo engasukeki (ngendlela elula lapho ibuna) ye-papaverine. Ngobuhlungu obukhulu, singangeza ama-analgin amaningi noma i-baralgin.

Umthamo ubalwa ngokuhlukile ngawodwana esigulini ngasinye.Ukuvela okungafani ngendlela yesicanucanu nokuhlanza kwenzeka, noma kungenzeki kaningi. Ngakho-ke, bonke odokotela bomtholampilo wethu abavumeli abanikazi ukuba babuye emakhaya nezigceme zabo, ukuze sikwazi ukunikeza usizo ngemiphumela engathandeki. Abanikazi abaningi baphawula ukuthi izilwane ezifuywayo zilala kakhulu ngemuva kwemijovo. Ungomunye wemiphumela emibi.

Kuzoba nokuthakazelisa:

Iqiniso ngukuthi i-papaverine ngandlela thile icindezela isistimu yezinzwa futhi amakati azizwa elele. Kuhamba, akufanele ukhathazeke ngakho. Kepha ngaphambi kokujova i-papaverine, sibheka imingcele ye-biochemical yegazi (i-urea, i-creatinine, nabanye) ukwenza isiqiniseko sokuthi ikati noma ikati lizongena kulomjovo. Ukwehluleka kwezinso, sizama ukungasebenzisi i-papaverine. Ngokuvamile, lesi sidakamizwa sisebenza kahle futhi sisiza ukuba khona kweziguli zethu ezinemilenze emine, kepha ukusetshenziswa kwaso kufanele kuphathwe ngokucophelela okukhulu.

I-Papaverine hydrochloride ine-antispasmodic effect, efaka ukukhululeka kobuhlungu. Isilwane ngokusobala iba lula ngemuva kokusisebenzisa. Kodwa-ke, kubalulekile ukukhumbula ukuthi awusoze wazikhohlisa, ngoba lokhu kungadala ukulimala okukhulu kwikati lakho olithandayo. Ngokukhula kwanoma yisiphi isifo esilwaneni, kufanele uthintane nodokotela wezilwane ngokushesha ukuthola usizo olukhethekile. ”

Lapho kusetshenziswa i-papaverine

imisipha ebushelelezi yemisipha ebangelwa izifo zomgudu we-biliary (cholecystitis, cholangitis, cholangiolithiasis, cholecystolithiasis, pericholecystitis, papillitis),

imisebe yemisipha ebushelelezi yepheji lomchamo nge-cystitis, uro- nephrolithiasis, i-pyelitis, i-tenesmus yesinye.

Ngokwengeza ekwelashweni okuyinhloko, umuthi ungasetjenziswa ukwehlisa umsipha wemisipha ebushelelezi ebangelwa izifo zesisu namathumbu. Izinkomba ezisetshenziswayo yilezi: ama-peptic ulcer, izinhlobo ze-meteoric ze-spastic colitis, kanye ne-IBS yokuqunjelwa, ama-pyloric spasms kanye ne-Cardia.

Umphumela wemithi

I-Myotropic antispasmodic kanye ne-antihypertensive drug.

Ivimbela i-phosphodiesterase futhi ibangela ukunqwabelana kwe-cyclic 3 ', 5'-AMP esitokisini kanye nokwehla kwezinga leCa2 +.

Yehlisa ithoni futhi ivuselele imisipha ebushelelezi yezitho zangaphakathi (ipheshana lesisu, isistimu yokuphefumula kanye ne-genitourinary) nemithambo yegazi.

Kubangela ukwanda kwemithambo yegazi, kusiza ukwandisa ukuphuma kwegazi, kufaka phakathi ubuchopho.

Kwimithamo emikhulu, kunciphisa injabulo yemisipha yenhliziyo futhi kwehlise ukwenziwa kwe-intracardiac.

Umphumela ohlelweni lwezinzwa oluphakathi awuvezwa kahle (kumthamo omkhulu unomphumela wokuhambisa).

I-Pharmacokinetics

Izinga lokutholwa liphezulu, i-bioavailability imaphakathi -54%. Ukuhlanganiswa kwamaprotheni e-plasma - 90%, kwakha izakhiwo ezinzile ezinama-serum albhamuin.

Sisatshalaliswa kahle kwizicubu zomzimba, singena kwizithiyo zomlando.

Kudalwe emzimbeni wesibindi.

Ukuqedwa kwesigamu sempilo kungamahora we-0.5-22 (anganwetshwa aze afike emahoreni angama-24). Igcotshwa ikakhulukazi yizinso ngendlela yama-metabolites.

Isuswe ngokuphelele egazini ngesikhathi se-hemodialysis.

Ukweqisa

Izimpawu: i-hypotension, ukungaboni kahle (ukubona okuphindwe kabili), ubuthakathaka, ukozela, ukuncipha kwegazi, ikhanda, isicanucanu, ukuqunjelwa, ukujuluka, ukungezwani komzimba. Uma ngephutha uthatha imithamo emikhulu kakhulu ye-papaverine, umphumela onobuthi wesidakamizwa ngendlela ye-arrhythmias, ephelele noma ingxenye yebhulokhi ye-atrioventricular kungenzeka.

Ukwelashwa: ukuhoxiswa kwezidakamizwa, ukwelashwa okubonakalayo. Nikeza ukuqubuka kwesisu, ukuthatha ama-enterosorbents, ukugcina umfutho wegazi.

Ukusebenzelana kwezidakamizwa

Ngokusetshenziswa kanyekanye ne-anticholinergics, kungenzeka ukuthuthukisa imiphumela ye-anticholinergic.

Kukholelwa ukuthi ngokusetshenziswa kanyekanye ne-alprostadil ekuphathweni kwe-intracavernous, kukhona ubungozi be-priapism.

Kunemibiko yokwehla kokusebenza kwe-levodopa ngokusetshenziswa kwayo kanyekanye.

Yehlisa ukusebenza kwe-methldopa.

Ngokuhlanganiswa ne-barbiturates, umphumela we-antispasmodic we-papaverine uyathuthukiswa. Lapho kuhlanganiswa nama-antidepressants ama-tricyclic, i-procainamide, i-reserpine, i-quinidine, ukwanda komphumela we-hypotensive we-papaverine kungenzeka.

Uhlobo lwedosi

Ngaphakathi - 40-60 mg izikhathi ezingama-3-5 / ngosuku.

Ngokubanzi - 20- 40 mg izikhathi ezi-2 / ngosuku.

Lapho i / m, s / c noma ku / ekwethulweni komthamo owodwa kubantu abadala ngu-10-20 mg, isikhathi esiphakathi kokuphathwa singekho ngaphansi kwamahora angama-4. Ezigulini esezikhulile, umthamo wokuqala wokuqala awudluli kwi-10 mg. Ezinganeni ezineminyaka eyi-1 kuya kwengu-12, umthamo owodwa omkhulu ngu-200-300 mcg / kg.

Inhloso, izakhiwo kanye nenqubo yokusebenza kwePapaverine

I-Papaverine isidakamizwa esinomphumela we-antispasmodic. Yathola igama layo kuyi-papavere yesiLatini - "poppy", ngoba kwakuvela opium lapho usokhemisi waseJalimane uGeorg Merck ayimisa le alkaloid ngonyaka we-1848.

Lapho ungenile, i-papaverine iphumula imisipha ebushelelezi. Umphumela utholakala ngokuvimbela i-phosphodiesterase, i-cycloadenosine monophosaft inqwabelana emangqamuzaneni, futhi okuqukethwe kwe-calcium kuyancipha, ngokuhlukile. Konke lokhu kuholela ekunciphiseni kwezwi lemisipha ebushelelezi yezitho zangaphakathi nemithambo yegazi. Imithambo inwebeka, ukuphuma kwegazi kuyathuthuka, kufaka phakathi ubuchopho, futhi umfutho wegazi uyancipha. I-antispasmodic iyakwazi ukuba nomphumela wokuvusa amandla ohlelweni lwezinzwa lapho usebenzisa imithamo emikhulu.

Izinkomba zokusetshenziswa

Izifo lapho kusetshenziswa khona iPapaverine:

• cholecystitis - ukuvuvukala inyongo,
• cholangitis - ukuvuvukala kwemigqa ye-bile,
• amatshe endunduma nemifino, izinso, isinye,
• i-papillitis inqubo yokuvuvukala ku-papillae yesisu,
• cystitis - ukuvuvukala kwesinye,
• isilonda se-peptic
• i-spastic colitis.

Ungayiphatha kanjani ikati ngesidakamizwa?

IPapaverine itholakala ngezindlela ezimbili: amaphilisi nomjovo. Isixazululo sithululelwa kuma-ampoules engilazi we-2 mm, ahlanganiswe ngezingcezu eziyi-10. kuhlanganiswe. Amathebulethi angama-40 mg atholakala kumaphakeji ahlukene, ahluka ngobuningi. Ngaphezu kwalokho, kusekhona ama-suppositories angama-rectal we-20 mg, kepha emithini yezilwane ayisetshenziselwa ekwelapheni amakati.

Amathebhulethi: umthamo, imvamisa yokuphatha, isikhathi sokwelashwa

Umthamo womuthi ubalwa nodokotela wezilwane ngokuya ngesisindo sesilwane. Ngokuvamile, i-1 kg idinga i-1-2 mg yesidakamizwa amahlandla ama-2 ngosuku. Imvamisa, inkambo yokwelashwa ayithathi izinsuku ezingaphezu kwezingu-7, kepha ubude besikhathi buncike kulesi sifo kanye nesimo sesilwane.

Iphilisi livame ukunikezwa ekuseni nakusihlwa, ngaphambi kokulala. Umuthi unokunambitheka okumunyu, ngakho-ke ikati lingenqaba ukuligwinya. Uma isilwane singakhethi, ungabeka lethebhulethi eduze kwesitsha noma usike bese uxuba nokudla. Kodwa-ke, amakati amaningi atholakala ukwenqaba ukudla kunokudla umuthi obabayo.

Uma kungekho okusizayo, futhi akunakwenzeka ukondla iphilisi kwikati, umuthi unikezwa ngempoqo. Babambe isilwane ngezandla, bavula imilomo yabo futhi babeka uPatverine ngangokunokwenzeka olimini. Ngenxa ye-reflex yokugwinya, ikati alinakho ukukhetha ngaphandle kokugwinya iphilisi. Ngaphezu kwalokho, idivaysi ekhethekile ingahle ikusize - i-tablet-feeder.

Izinhlobo zamakhemikhali ze- “Papaverine” zamakati

Kunezindlela ezintathu zokukhishwa kwezidakamizwa:

• Isixazululo somjovo, umphumela we-antispasmodic ohlala amahora ayisithupha kuya kwayisishiyagalombili, ufakwa engxenyeni engilazi yamamililitha amabili, kuthiwe kufakwe izimbumbulu eziyishumi ebhokisini linye,
• amaphilisi asetshenziswa kaningi ngenxa yokuthi umphumela wawo we-analgesic uhamba kancane, 40 mg ngamaphakeji ahlukile,
• kusetshenziswa ama-rectal suppositories (ama-milligram angama-20) uma kungeke kwenzeka ukujova futhi akunakwenzeka ukunikeza isilwane iphilisi.

Izici zemvelo zesidakamizwa

Umuthi ubangela ukuvela kwe-phosphodiesterase, esiza ukunciphisa ukugcwala kwama-calcium ion kwezicubu zemisipha, kufaka isandla ekwehliseni kobuhlungu. Ngakho-ke, izicubu zingakhululeka futhi zingabangelwa, zibuhlungu kakhulu, izitho zabo.

I-spasm ingavimba umsebenzi wanoma yisiphi isitho sangaphakathi, njengomphumela lapho ukusabela kungavela ngendlela yokopha, izinhlungu, ukukhathazeka. Lapho izinhlungu zincipha, ukuhamba kwegazi kuyathuthuka futhi ikati lithola ukuphumula okulindelwe isikhathi eside.

Funda nokuthi ungayisebenzisa kanjani iDrotaverin kukati.

Impilo yeshelufu nezimo zokubeka

Impilo yeshelf umuthi, kuya ngohlobo lokukhululwa:

• Isixazululo - iminyaka engu-2,
• amaphilisi - Iminyaka emi-5,
• ama-suppositories - iminyaka engu-2.

IPapaverine ayidingi siqandisi ukuze igcinwe - lo muthi ugcinwa endaweni emnyama emazingeni okushisa angama-25 ° C kuyo yonke impilo eshalofini.

Zonke izifo zomgudu wesibeletho noma uhlelo lwezitho zofuzo kumele ziphathwe ngokuphelele, kepha okokuqala kudingeka udambise izinhlungu ukuze isilwane singaholi. UPapaverine ulungele lokhu.

Khipha ifomu nokwakheka kwezidakamizwa

I-drug no-spa itholakala ngezindlela ezimbili:

• Amacwecwe. Anombala ophuzi okhanyayo, umthunzi ungaba owolintshi noma luhlaza okotshani. Ifektri eqopha "i-Spa" ikhonjiswa ngakwelinye uhlangothi lwethebhulethi. Iphakethe liqukethe inani elihlukile lomuthi, kusuka ezingxenyeni eziyisithupha kuya kweziyi-100.
• Isixazululo. 2 ml ingilazi ethambile ingilazi. Kufakwe ebhokisini lekhadibhodi ngaphakathi kwepulasitiki. Inani lama-ampoules kwiphakeji elilodwa lingaba izingcezu ezi-5 noma ezingama-25.

I-No-shpa (drotaverinum)

Umuthi osebenzayo yi-drotaverine hydrochloride (40 mg).

Umuthi one-antispasmodic, vasodilator, hypotensive effect

I-No-spa antispasmodic. Izinto ezengeziwe: i-magnesium stearate (3 mg), i-povidone (6 mg), i-talc (4 mg), isitashi sommbila (35 mg), i-lactose monohydrate (52 mg).

Umuthi we-papaverine ungatholakala ngezinhlobo ezintathu:

Ikativerine ikati nge-cystitis. Papaverine injekete kwikati

Umuthi osebenzayo onegama elifanayo "i-Papaverine chloride" ubhekise kuma-alkaloid aqinile aqhakambisa ukuphumula kwayo yonke imisipha nezitho zangaphakathi ngaphandle kokukhetha, okukuvumela ukuthi ugxilise i-syndrome yezinhlungu ngokushesha.

Ngenxa yomphumela wawo obucayi kakhulu emzimbeni phezu kokuphathwa, i-Papaverine inikezwa ikati kaningi kakhulu kune-Nosh-Pa, futhi ebhekisela kuma-antispasmodics aqinile, futhi konke ngoba akukho zimo zezinkinga ezirekhodiwe ngenxa yokusetshenziswa kwayo. Ngokwemvelo, lolu lwazi lufanelekile uma kungukuthi umthamo ofanele wePapaverine wamakati ubonwa, ongabekwa udokotela kuphela, kuya ngohlobo lwe-pathology kanye nethuba lokukhula kwayo. Ngokuqondene nokukhethwa phakathi kwale antispasmodic ne-Nosh-Pa yendabuko, iningi lithanda i-Papaverine yamakati ngezizathu ezilula zokuthi alicunuli i-paresis yesikhashana yezitho zomzimba wesinyamazane.

Vele, uma ufunda le migqa, kuzoba nabantu abaningi abenqaba ukubandakanyeka kukaNosh-Pa kuzinkinga ezinjalo. Kodwa-ke, izibalo ziphakamisa okuhlukile futhi kungenzeka ukuthi sikhuluma ngokunyamalala kwesikhashana kwemisipha okubangelwa ukushaqeka kobuhlungu, isilwane esihlangabezana nakho lapho umuthi usungenwa enkingeni. Kunoma yikuphi, lapho usebenzisa i-Papaverine amakati, umthamo wawo uhambisana ngokuphelele nesisindo sesilwane, imiphumela emibi kangako, ngisho naleyo yesikhashana, ayikaze ibonwe.

Kodwa-ke, umuntu akufanele acabange ukuthi le antispasmodic ayinangozi ngokuphelele futhi ayikwazi ukudala ingozi enkulu esilwaneni. Ngakho-ke, ukungabekezeleli komuntu ngamunye, ukwehluleka kwesibindi, kanye nezinkinga zesistimu yezinhliziyo (okusho ukuthi ukuqhuba kwayo) kungaba yinto ephikisayo ekusetshenzisweni kukaPapaverine Chloride. Ngaphezu kwalokho, kungcono ukugwema ukusetshenziswa kwalesi sidakamizwa noma ukusisebenzisa ngaphansi kokuqapha ngokucophelela ukuze uqhubeke nokuqapha ukusondela kwesilwane, noma kunalokho ukusabela kwaso, uma sinezinkinga ezinkulu ngezinso nezindlala ze-adrenal.

Ngaphezu kwalokho, ngokwengxenye akunconywa ukufaka i-Papaverine kwisilwane esibhekene nengcindezi enkulu noma esesimweni sokushaqeka. Akukafaneli sikhohlwe ngemiphumela emibi engenzeka noma ngabe ibuzwa umuthi ojwayelekile.

Ngakho-ke, ukozela, i-tachycardia, isicanucanu kuze kufike ekuhlanzeni, kanye nokwehla okukhulu komfutho wegazi kungasabela ekuphatheni okuphathelene ne-"Papaverine chloride" (lolu phawu lungakhuphuka lapho umthamo wedlula). Kungakho kunconyelwa ngokuqinile ukwenza kuphela ngokwemiyalo, futhi okungcono kakhulu ngokuya ngezincomo zikadokotela oholayo. Ngokusho kokufakwa kolwazi, "i-Papaverine" kwikati (ifomu lokukhishwa libonisa ukuthi ama-ampoules we-2 milliliters ngamunye) kufanele aphathwe ngokungahambi kahle. Ngaphezu kwalokho, injekishini eyodwa yamakati kufanele ifake kusuka ku-0,01 iye ku-0,05 amagremu umuthi.

Ukuze uthole ukuzwisiswa okunembe kakhudlwana kwevolumu ye- "Papaverine" kwikati (umthamo), kuyadingeka ukuqondiswa imininingwane efana nesisindo nobudala besilwane, kanye nohlobo lwesifo saso. Kwesinye isikhathi lesi sidakamizwa sisetshenziswa ngokuhlangana namanye ama-analgesics, esiza ukukhulula i-pain pain syndrome ngesikhathi esifushane, esibaluleke kakhulu ku-urolithiasis ne-cystitis, lapho isilwane singakwazi ngisho nokuchama ngokujwayelekile. Ngaso leso sikhathi, ungakhohlwa ngomqondo obalulekile onjengokuthi isikhathi sokusebenza kukaPapaverine Hydrochloride, esivame ukungadluli amahora angama-5-6.

Njengoba wazi, amakati asebenze inqubo ephoqelelwe yokuxoshwa awela eqenjini eliyingozi okokuqala, futhi i-hypothermia evamile ngisho nokujwayelekile yanele ukuthuthukisa i-cystitis. Ezimweni ezinjalo, kukhona ukubambezeleka komchamo (kwesinye isikhathi ukungabi bikho ngokuphelele), kanye nevolumu yayo encane ene-inclusions yamagazi ngokuchama okuvamisile. Kungokwemvelo impela ukuthi lezo zimpawu zivuse isifo esibuhlungu kakhulu, zibangele ukuhlupheka okungathi sína esilwaneni, ngakho-ke, isilinganiso sokuqala sendlela yokuthola isimo sesilwane esigulisayo ukuphulukisa umsele wayo wokuchama. Futhi uma i-catheter ibekwa ngaphansi kwe-anesthesia ejwayelekile, khona-ke ngokuzayo izidakamizwa ezinjengoPapaverine ezisiza ukususa imizwa ebuhlungu.

Ngakho-ke, imvamisa kakhulu “i-Papaverine” yamakati isetshenziswa ezinsukwini ezintathu zokuqala (kabili ngosuku ngokungabonakali ngenani lomjovo owodwa kuze kufike kumamililitha ayi-0.5) ngokuhambisana nezimali ezenzelwe ukungabusizi ubuhlungu, kepha ngqo ekwelapheni lesi sifo.

Isibonakaliso esihle sibukwa ukungabikho kobuhlungu ngenkathi uchama ngemuva kokumiswa kokusetshenziswa kwalesi sidakamizwa. Endabeni ye-catheterization, izikhathi ezingenhla zingandiswa ngezinsuku ezimbalwa.

I-Papaverine iyisidakamizwa esakhiwe kahle esisebenza nge-antispasmodic hhayi kubantu kuphela, kodwa nasenkambisweni yezilwane (ikakhulukazi, maqondana namalungu omndeni we-purring).

Amandla we-overdose

Awukwazi ukusebenzisa i- "Papaverine" ngaphandle kokubonisana nokuyalela udokotela wezilwane!

Ngenxa yokubalwa okungalungile kwevolumu yesidakamizwa isisindo sesilwane ngasinye, kungenzeka ukuba ne-overdose. Imiphumela yayo ingaba:

• ukulahleka kombono (okwesikhashana noma okuhlala njalo),
• isizungu,
• umbono ongahambi kahle (ukufiphaza),
• ikhanda, isicanucanu,
• amakhanda ezinsikazi zezinja,
• sedation enamandla
• kwehle ukwehla kwesicubu senhliziyo.

Uma kwenzeka kweqisa ngokweqile, kuyadingeka ukumisa ngokushesha ukusetshenziswa komuthi futhi, ngokushesha okukhulu, uwususe emzimbeni futhi uqiniseke ukuthi umfutho wegazi uyagcinwa. Kunikezwe ukukhishwa kwesisu (lapho uthatha amaphilisi) futhi uthatha ama-enterosorbents.Ungavumeli isilwane sidle size sihlolwe nguchwepheshe.

Yini engcono kunokujova noma amaphilisi

Imvamisa, lo muthi ubekwa ngendlela yemijovo, futhi lokhu kubangela ukuthukuthela kwabanikazi abaningi bamakati. Kukholelwa ukuthi i-drotaverine ngendlela yesisombululo somjovo ibangela ukuba isilwane siqede noma silinganise imilenze yokuqina okhubazekile. Abanye abantu bacabanga ukuthi kungcono ukusebenzisa iPapaverine, kepha lokhu akunjalo, ngoba lesi sidakamizwa naso sise-antispasmodics, futhi sinomphumela ofanayo emakati.

Kungakhathalekile ukuthi umuthi uphathiswe muphi umuthi, isilwane singabekezelela izingxenye ezithile zomzimba, ukungahambi kahle komzimba, kanye nokuhlasela kwemizwa kungenzeka kulowo muthi.

Ngaphezu kwalokho, ukujova kweNo-Shpy kubuhlungu kakhulu, kanti nesilwane kungenzeka sisesimweni sokuthuthumela. Ukwedlula okuthe xaxa komthamo we- “No-Shpy”, ikati lingaba nemiphumela engemihle, nemibi.

Abanye odokotela bezilwane banquma lesi sidakamizwa ngendlela yepilisi. Kepha akukhona konke okushelelayo kuye. Izibhebhe zinokunambitheka okunyanyekayo, okubabayo, futhi alikho ikati elilodwa elizokugwinya ngokuzithandela. Kodwa namanje ukuba lusizi kungcono kunemiphumela engenzeka yokulimala.

Isilinganiso semithi

I-millilita eyodwa yesidakamizwa iqukethe amamiligremu amabili ento esebenzayo (papaverine hydrochloride), amanzi akhethekile wokujova, D, L-methionine kanye ne-disodium edetate. Umthamo uhlala ukhethwe ngudokotela kuphela. Lokhu ukwenza ngokuya ngesithombe somtholampilo sesi sifo sekati, uhlobo lokukhululwa kwalo muthi, iminyaka nesisindo sesilwane.

• Ngendlela yemijovo, amakati ayelulekwa ukuthi aphathe kuphela amagremu angama-0,01-0.05, ngokunqenqemana, ngokulimala, kabili ngosuku.
• Uma kwathathwa isinqumo sokusebenzisa amaphilisi, asetshenziswa ngenani lama-milligrams ayi-1,2-1,5 ngekhilogremu ngayinye yesisindo sesilwane, ngomlomo, kabili ngosuku.
• Amakhandlela (isigidi esisodwa noma ezimbili ngekhilogremu yesisindo), kabili ngosuku, kepha kuvunyelwe ukusebenzisa izingcezu ezine ngosuku.

Ukujova kuphi futhi kanjani?

Ungawungena umuthi ngokunqenqemana (emabeleni), ngaphakathi nangaphakathi (ngethanga).

Udokotela kufanele afake umjovo emtholampilo wezilwane ukuze isilwane singabi nengcindezi yomjovo ongalungile nokwesaba komnikazi wokujova lojovo olufanayo, kanye nokuvikela ukulimala isilwane.

Esibhedlela, amakati aziphatha ngokwenqena futhi anikeze amakhono okukhwabanisa adingekayo, futhi ekhaya, eqaphela ukuthi umuntu uyamhawukela, angabalekela ezandleni zakhe ngenalithi emzimbeni wakhe noma aze ayigobe, okungaholela ekulimaleni kwesilwane.

Ukujova okungalunganga kungalimaza isilwane sakho, ngakho-ke ukusetshenziswa kwaso kumele kusondelwe kakhulu futhi ngokubonakalayo nangokusho okukhulu.

Inkambo yokwelashwa ihlala inqunywa kuphela ngudokotela wezilwane ohambelayo. Isikhathi somuthi sincike ezicini eziningi, okuyinhloko okuyisigaba sesifo nobunzima baso. Imvamisa, inkambo yokusebenzisa umuthi ayidluli izinsuku eziyisikhombisa, kepha kunezimo ezithuthukile lapho isikhathi somuthi sikhuphuka.

Umuthi unesibalo esikhulu se-contraindication nemiphumela emibi. Qiniseka ukuthi uzitadisha ngaphambi kokubaphatha isilwane. Awukwazi ukusebenzisa i- "Papaverine" nge:

• ukwehluleka kwesibindi
• glaucoma
• ukwethuka nengcindezi,
• umsebenzi okhubazekile we-adrenal.

Ngokuqapha, kuvunyelwe ukusebenzisa ngama-arrhythmias anjalo nama-arrhythmias, kepha ngemuva kokuphathwa, isilwane kufanele sibe ngaphansi kokubhekwa. Ungasebenzisi ekugugeni nasezinhlwaneni ezincane (kuze kube izinyanga eziyisithupha).

Imvamisa izilwane zibekezelela isenzo sale nto ye-antispasmodic, kepha kunezimo zokungabekezelelani komuntu ngamunye kanye nezinkinga ezithile ngendlela yemiphumela emibi.

Imiphumela emibi engaba khona:

• isicanucanu,
• ukunganaki, ukozela,
• ukuqunjelwa
• ulaka nokwesaba okwandayo,
• umjuluko osindayo
• ukuphazamiseka emsebenzini wenhliziyo,
• kwehlisa umfutho wegazi.

Imvamisa, imiphumela emibi ibonwa kuphela ezimeni zokweqa umthamo. Kwesinye isikhathi, umuthi ngokwezigaba awuhambelani nesilwane, kepha asikho isizathu esibonakalayo. Kulokhu, udinga ukubonana nodokotela wezilwane mayelana nokubuyisela umuthi komunye oqukethe izinto ezihlukile ezisebenzayo.

Okuqhamuka uma udla imishanguzo

Umuthi ubekezelelwa kahle ngamakati. Kepha i-overdose ingadala imiphumela emibi, ekhonjiswa isicanucanu, ukugabha, ukozela, ukuqina. Ngenxa yamandla emithi yokuthinta isimo sohlelo lwezinzwa, izinkinga zesikhashana zokuzwa nokubuka zingenzeka.

Ngesikhathi sokulashwa, kubalulekile ukubona isilwane. Lapho kuvela izimpawu ezingathandeki, kufanele uyeke umuthi futhi uthathe isilwane kuye uchwepheshe. Uma kungenzeki ukufinyelela emtholampilo wezilwane emahoreni angama-2-3 alandelayo, kuyadingeka ukuhlanza isisu sekati ngesixazululo esibuthakathaka se-potanganum permanganate futhi unikeze namalahle ocushiwe noma enye i-sorbent. Ngaphambi kokuhlolwa ngudokotela wezilwane, isilwane akufanele sondliwe.

Ungayinikeza kanjani ikati umjovo, umthamo

Ukuze unciphise ukusabela okungalungile komzimba, inaliti kufanele ifakwe ngokujulile ngangokunokwenzeka emisipha, umuthi kufanele uphathwe kancane. Umthamo ubalulekile lapha. I- “No-Shpa” kuma-ampoules amakati kuyindlela engakhethwanga kangako, kepha uma udokotela wezilwane ebeka imijovo, kunezizathu zalokhu.

I-0.1 mg yesisombululo ibalwa ngekhilogremu yesilwane ngasinye. I-ampoule eyodwa ye- “No-Shpa” iqukethe ama-2 ml, hhayi ama-0,2 - leli yiphutha labanikazi abaningi abangenalwazi bamakati abazojova isilwane okokuqala. Imvamisa, umjovo wenziwa kabili ngosuku ngokuphumula kwamahora ayi-12. Kodwa nokho umthamo ngqo, inani lemijovo ngosuku nesikhathi sokulashwa sizonikezwa udokotela kuphela.

Ngokuqondene nokwelashwa kwe-cystitis eyingozi emakati, umthamo wesidakamizwa ungaba mkhulu - u-0,2 mg ngekhilogremu ngayinye yesisindo sesilwane. Kepha i- "No-Shpa" akuyona ukuphela kwesidakamizwa esinqunyelwe lesi sifo, umuthi usetshenziswa ekwelapheni okuyinkimbinkimbi. Umuthi ochaziwe udambisa isimo sesilwane ngokunciphisa cramping, ukunciphisa noma ukuqeda ubuhlungu nhlobo.

Imithamo nendlela yokuphatha

Umuthi akufanele unikezwe ezimweni ze:

• Ukwehluleka kwangempela
• I-Glaucoma,
• Ubudala besilwane, kungaba ne-hyperthermia,
• Iminyaka efinyelela ezinyangeni ezi-3
• Isilwane sinokuzwela okwengeziwe nge-papaverine,
• Ukulimala ekhanda
• Ukwehluleka kwangempela
• I-Hypothyroidism,
• I-Hyperplasia
• I-Tachycardia.

Ngaphambi kokuthatha umuthi, kufanele ngaso sonke isikhathi ubonane nodokotela wezilwane, akufanele unqume ukwelashwa ngokwakho.

Kufanele futhi udlule nohlu oludingekayo lokuhlola ukuthola imbangela yangempela yesifo sezilwane ezifuywayo.

I-antispasmodic ngesimo sama-suppositories

Amaphuzu abalulekile

1. Ikati lalizizwa ligula emotweni noma embukisweni, idali lidwengule indlebe yalo, lijaha amagundane ezwe, kodwa ikhithi losizo lokuqala lezilwane ligcinwe ekhaya esiqandisini - futhi yini ukusetshenziswa kwalo? Ukuhamba nohambo nekati, ikakhulukazi uma kungekho mitholampilo yezilwane osendleleni, kufanele njalo uhambe nekiti lakho losizo lokuqala.

2. Ngaphezu kwalokhu okulandelayo, ikhithi yezilwane yamakati yindawo yokugcina ifolda enemiphumela yokuhlaziya okwenziwe, izindlela zokupheka nezokwelashwa, ipasipoti yezilwane kanye neminye imibhalo. Ukwenza lula umsebenzi kadokotela, la maphepha azodinga ukuthatha nawe. Kepha azisizi ngalutho kumnikazi wazo: izifo eziningi zithambekele ekubuyeni, amanye amakati athande ukukhotha ezinye ikakhulu “iminyuzi eyintandokazi”, ezinye zihlala zilwa. Lokho wukuthi, izimo zivame ukuphindaphindwa, futhi kulokhu, ukuhlinzeka usizo kumakati kulula uma une-iresiphi yakudala enamagama nomthamo wezidakamizwa onawo. Vele, udinga ukubona udokotela kunoma yikuphi, ikakhulukazi uma kukhulunywa ngesifo esingelapheki. Kepha ukuba neresiphi yakudala ekhona, ungamisa, isibonelo, ukumisa ukuhlaselwa kwe-ICD, ukuvikela ukunqandeka kwe-ureter - ukuhlanganiswa okukhulu ebhange lezingulube lomnikazi ofanele.

Kubalulekile ukuthi ikhithi yosizo lokuqala yezilwane ilungele ukusetshenziswa. Sithatha umaki ogqamile: kunezinyanga ezintathu esele ngaphambi kosuku lokuphelelwa - faka i-squiggle yamafutha esivalweni noma eceleni kwegama

Usizo oluphuthumayo kumakati - isimo ezimweni eziningi siyacindezela, ungakhohlwa ukubheka okuhlanganiswayo. Futhi ebona umaki, umnikazi ngokuqinisekile uzokhumbula ngezindlela zokuphepha futhi ahlole usuku lokwenziwa kwalo muthi.

4. Imvamisa usizo lokuqala lukati luhlehliswa ngenkathi umnikazi wezinzwa eqhubukusha ebhokisini eligcwele izimbiza, amabhodlela, izihlakala, amashubhu, ukufunda amagama nokukhumbula ukuthi yini. Ukugwema lesi simo, le mishanguzo kufanele ihlelwe emabhokisini amancane, ukusayina izembozo: ama-painkillers, sedative, heestatic, njll. Futhi ke mane ufake la mabhokisi ebhokisini lezicathulo elikhulu, ngokwesibonelo.

5. Esembozweni sebhokisi kufanele kubhalwe izingcingo zabadokotela bezilwane, phakathi kwazo okufanele kube izinombolo zalabo abasebenza ubusuku nemini. Esimweni esiphuthumayo, lapho "ukubambezeleka ukufa kufana" (ukopha kakhulu, into engaphandle komphimbo, ukushaqeka kwe-anaphylactic), udokotela uzochaza ngocingo ukuthi ulunikeza kanjani ikati usizo lokuqala. Lokhu kubaluleke kakhulu uma umnikazi engenalwazi futhi kungukucabanga ngokweqiniso kuphela ukuthi, ngokwesibonelo, ukujova noma ukuhlanza.

Yini uNo-Shpa?

Le yi-antispasmodic eqinile, ethandwa kakhulu futhi ithembekile. Lo muthi wenzelwe abantu, kepha usetshenziswa kabanzi ekwelapheni kwezilwane. Umuthi unamandla kakhulu, futhi awukwazi ukusinikeza isilwane sakho. Azikho imithamo ye-No-Shpy ebekiwe yamakati kumanyuwali, ngaphandle kokuthi uchwepheshe akekho ongawabala kahle. Yini esongela ukweqisa kwesilwane? Okuningi kulokhu ngokuhamba kwesikhathi, kepha okwamanje, ake sibheke ukwakheka kwalo muthi.

Intengo nezimpawu

Intengo yezidakamizwa iyahluka. Umgomo wamanani ngokuya ngesibalo samathebulethi kwiphakheji nakuyo iphakethe ngokwayo. Amathebulethi angathengwa kusuka kuma-ruble angama-67 kuye kwangama-500. IPapaverine ishibhile ngandlela thile, inani eliphansi ngama-ruble ayi-10 (amaphilisi ayi-10).

Uma udinga ukufaka i-no-shpu noma i-papaverine, ungakhetha ama-analogues:

Sengiphetha, ngifuna ukusho ukuthi kuyadingeka ngaso sonke isikhathi ukunakekela isilwane sakho osithandayo. Uma ubona izinkinga, kufanele uthintane nodokotela wezilwane onolwazi ngokushesha. Uma ungenalo ithuba elinjalo, ngakho-ke kufanelekile ukunikeza amaphilisi kuphela uma usifunde kahle lesi sidakamizwa.

Ukuqokwa kwe-No-Shpy ezilwaneni

Ngokuvamile amakati "No-Shpu" anqunyelwe

• cystitis
• isifo sokuqaqamba kwamalunga
• urolithiasis,
• isifo sezinso nabanye abaningi.

Umuthi ngempumelelo futhi ususa ngokushesha izikhala zemisipha ebushelelezi yezitho zomzimba, ngaleyo ndlela unciphise ama-syndromes ezinobuhlungu. Imvamisa, isidakamizwa sisetshenziselwa nezifo zesisu (i-gastritis, ulcer, i-colitis, ukuqunjelwa noma isifo sohudo).

Kunanoma yibuphi ubuhlungu futhi nganoma yiluphi uhlobo, umthamo weNo-Shpy wamakati kufanele ubalwe ngawodwana, futhi udokotela wezilwane kuphela ongakwenza lokhu! Kubukeka kumuntu ukuthi umuthi awunangozi, futhi kunzima ukuwuphuza ngokweqile. Kunamaphilisi amaningi wekati, futhi i-overdose ingadala ukufa kwesilwane.

Ukwelashwa

Uma ikati linorhudo ngenxa yokudla okungenampilo, kufanele ingafakwa kokudla. Kuyadingeka ukuhlinzeka isilwane ngesimo sokuphumula. Ngosuku lokuqala lokwelashwa, kitten kufanele igcinwe ekudleni okulambile, ngosuku lwesibili ungakwazi ukunikeza ukudla okuncane. Nikeza ukufinyelela okuqhubekayo kumanzi ahlanzekile, ahlanzekile. Ukudla kufanele kulandelwe okungenani inyanga.

Imithi

Ukwelapha isifo sohudo, unganikeza ama-kitten akho. Umphumela omuhle unikezwa i-smecta yezingane, i-enterosgel, i-enterofuril yezingane (ukumiswa), i-carbon eyenziwe yasebenza. Isifo sohudo sekati singalashwa ngesisombululo sikaRegidron noma amanzi anosawoti kancane (isixazululo esingu-8.5%), sisebenzisa isisombululo esikhundleni samanzi. Uma isilwane senqaba ukuphuza ngokwakho, ungathela isisombululo ngesirinji.

Ungabaniki ama-antibiotics kanye nama-sulfonamides uma lokhu kuyizisu ezivamile. Izidakamizwa ze-antibacterial zingaholela ezinkingeni, njengoba zibhubhisa i-microflora yamathumbu.

Njengomuthi, ama-probiotic anganikezwa, ngokwesibonelo, i-bifidobacteria, lactobacilli. Umuthi omuhle we-homeopathic Elvestin, ofanele ama-kittens amancane: ejwayelekile ukugaya futhi usiza ukuqinisa ukungatheleleki. IBifidumbacterin neVetom nazo zilungele izingane.

Amakhambi esintu

Ungaphatha i-kitten ngama-decoctions, ubenze kusuka elayisi, ifilakisi, amagxolo we-oki noma i-oatmeal. Kuzoba wusizo ukuphuza itiye le-petty nge-chamomile noma i-hypericum. Ngemuva kokwelapha isifo sohudo, i-kitten kufanele inikezwe ukudla okugayayo inyanga. Ungathenga okuphakelayo okwenziwe ngomumo kwezokwelapha, okusemgqeni ophuma cishe kubo bonke abakhiqizi, noma ukwenza imikhiqizo emisha.

Isiphetho

I-No-shpa yamakati ingumuthi ongaqondakali. Kuyasiza umuntu, umuntu - kubangele imiphumela emibi. Nokho, uma kunethuba elinjalo, kungcono uzame eminye imithi kuqala. Futhi yilapho kuphela, uma bengasizi, sebenzisa i- “No-Shpa”

Kwenzeka ukuthi ngemuva kokuthi udokotela wezilwane enikeze isiguli sakhe esinezinyawo ezine inkambo, umnikazi waso uhlala phansi phambi kwekhompyutha, ngakho-ke ... xoxani ngokuqokwa kwakhe ... futhi kuyamethusa lokho akufunda kubanikazi bezilwane "abanolwazi nabakhanyiselwe", uxolo, abanolwazi.

Futhi emva kwalokho, ukwelapha isisu ngemithi ebekwe udokotela ... isandla nje asisukumi ... Kepha akekho umuntu onesibopho sokwelashwa kwesilwane sakho, ngaphandle kwakho nokuthi udokotela "omubi" lowo, ngesizathu esithile angafuni ukuzithathela yena, ukwethusa wonke umuntu.

Futhi umnikazi onjalo "phakathi kukaScylla noCharybdis" ulenga ... Futhi abeluleki bethukile futhi bashiya, futhi udokotela usevele wethukile ukukholelwa.

Ezintweni zethu, sizozama ukuchaza ukungqubuzana okungenzeka ukuthi uhlangane nakho phakathi kwemiyalelo kadokotela wakho kanye nemibono esungulwe phakathi kwabathandi bezilwane "abanolwazi".

Namuhla sizokhuluma ngombono osabalele phakathi kwabathandi bekati (nabanye bezilwane) wokuthi ukusetshenziswa kwe-No-Shpa kulungiselelwe amakati. Futhi ngokuzenzakalelayo, ingxoxo imayelana nefomu lomjovo.

Kungani kuphikiswa?

Ngizocaphuna izimpendulo ezivame kakhulu zabaphikisi bokusetshenziswa kwezidakamizwa zeNo-Shpa emakati:

• Imilenze yangemuva lekati iyasuswa kuye
• Ikati ngemuva kokujova kweNo-shpa yahamba njengengubo futhi kungasindisa yena kuphela
• Ikati ngemuva kwe-No-shpy ingahlala izinyonga impilo
• I-No-spa ibangela i-paresis yezitho zomzimba we-pelvic
• Ikati lami lafakwa injanana no-No-shpu - wabe eseqala ukuhamba isikhathi eside futhi waxhuga

Njengoba ubona, okuvame ukubhekelwa phansi ukuphulwa kwekhono lokusebenzisa izitho zomzimba ngemuva kokulimala kwesidakamizwa seNo-Shpa noma ama-analogues aqukethe iDrotaverin hydrochloride.

Futhi njenge-analogues, inikezwa ngokushesha njenge-analog "ephephe kakhulu" - i-Papaverine hydrochloride.

Ngakho-ke, ngabaqalayo, sizozama ukuthola umehluko obalulekile phakathi kwale mishanguzo ukuze siqonde ukuthi kungani abanye bekholelwa ukuthi i-Papaverine hydrochloride iphephe kakhulu kumakati kune-Drotaverina hydrochloride (No-shpa). Ngale ndlela, kusukela manje kuqhubeke ngizosebenzisa igama elijwayelekile lezinto ezisebenzayo zokulungiselela kweNo-Shpa - iDrotaverina hydrochloride. Kuzoba ngokunemba ngokwengeziwe.

Ukuqhathaniswa kwezakhiwo zePapaverine neDrotaverin hydrochloride (isidakamizwa seNo-Shpa)

Inothi lomlando: IDrotaverina hydrochloride yadalwa lapho okwakhiwa khona isitshalo saseKhinoin ngonyaka ka-1961 ngesisekelo se-papaverine eyakhiqizwa efektri kudala. Ngakho-ke umsuka wezidakamizwa uvamile.

Indlela yokusebenza yesenzo se-antispasmodic: kuzo zombili i-Papaverine kanye neDrotaverin, umphumela we-antispasmodic usekelwe ekuvinjelweni kwe-encyme PDE-phosphodiesterase, ukugxilwa kwayo lapho izicubu kunquma ukusebenza kahle kweDrotaverin nePapaverine ekusebenzeni ngokomtholampilo. Ngaphansi kwethonya le-PDE inhibitors, inani le-cAMP (cycloadenosine monophosphate) esitokisini liyanda futhi inani le-ioni le-calcium liyancipha.Futhi ama-ion amancane we-calcium esitokisini, anciphisa amathuba okuqothuka kwe-fiber fiber. Umphumela uba ukwehla kwezinga lethoni nomsebenzi wezicubu ezibushelelezi zezitho zangaphakathi, okuholela ekuqedeni komsipha wazo.

Isikhathi namandla esenzo se-antispasmodic: eDrotaverin, impilo yesigamu ingamahora angama-7-12, futhi ePapaverine, amahora angama-1.5 - 2 kuphela. Ngasikhathi sinye, ukubukeka kwemisipha ebushelelezi eDrotaverinum kuphakeme izikhathi eziphindwe kahlanu kunaleyo esePapaverine.

i-pH yesisombululo somjovo: ubungako be-acidity yesisombululo esifakiwe sePapaverine neDrotaverin ngu-3-4.5, obonisa ukusabela kwendawo ngokuphathwa kwe-intramuscular and subcutaneous,

I-Metabolism yezidakamizwa: zombili lezi zidakamizwa zenziwa emzimbeni ezibindini futhi zichazwa yizinso njengama-metabolites - uPapaverine ngokuphelele, uDrotaverin - ngaphezu kuka-50% (cishe u-30% ukhishwa ngamathumbu nge-bile).

Ukungena kwezicubu: I-Papaverine yeqa isithiyo segazi-ubuchopho nakuzo zonke izicubu, iDrotaverin ayingene ohlelweni lwezinzwa oluphakathi futhi ayithinti isistimu yezinzwa ye-autonomic, idlula kancane emgoqweni we-placental.

Njengoba kungabonakala ekuqhathaniseni, ezinye izakhiwo zezidakwamizwa i-Papaverine hydrochloride neDrotaverin hydrochloride zisondele kakhulu, futhi umehluko okhona unquma izinkomba ngazinye zokusebenzisa umuthi othize.

Kodwa-ke, uma sikhuluma ngomshini obangela umphumela we-antispasmodic, izici zokusebenzisa umzimba kanye nomphumela oqondile emisipha ebushelelezi yezitho zangaphakathi nemithambo yegazi, khona-ke cishe ziyefana kuzo zombili izidakamizwa. Lokhu kusho ukuthi asikho isizathu sokusho ukuthi umuthi owodwa (i-Drotaverin) ungadala ukuvela ezinkomeni ezingeke zidalwe esinye isidakamizwa (Papaverine).

Yini umehluko ekuthini ukusangana kwamakati kuphathe izidakamizwa?

Konke kuncike kumaphoyinti ambalwa abalulekile esimweni nasekwenzeni komzimba wekati elithile:

• Ukuzwela kukati ngakunye nezidakamizwa
• Isimo sangaphambi kwekati ngaphambi kokujova i-antispasmodic
• Ukuphendula kwendawo lapho kwethulwa umuthi.

Ake sihlolisise ngalinye la maphuzu:

Ukuzwela kukati ngakunye nezidakamizwa

Njengoba sesishilo, i-phosphodiesterase enzyme (PDE) engaphezulu kwezicubu zesilwane, umphumela we-antispasmodic wanoma yisiphi isidakamizwa uzoba - okungenani uPatverine, ngisho noDrotaverin, kepha uPapaverine uzoba nokusabela okuphindwe izikhathi ezinhlanu.

Ukusabela okwenziwa yi-allergic and paradoxical of into ephilayo ekuphatheni izidakamizwa kutholakala kungakhathalekile ukuthi hlobo luni lwesilwane nohlobo lomuthi.

Ngaphezu kwalokho, akekho umuntu okhansulile ukusabela okuxakile komzimba wekati (njenganoma yisiphi isidalwa esinegazi elifudumele) ekwethulweni kwanoma yisiphi isidakamizwa. Imvamisa, ngokwesibonelo, amakati ngokufakwa kwezidakamizwa (intramuscular or intravenous) aqala "amagwebu".

Ukweqiwa okuningana kwamathe amisebe avela emlonyeni kungahlotshaniswa nokuphendula okucindezelayo kwesilwane esimweni somtholampilo wezilwane nenqubo yokwelashwa uqobo, kanye nomphumela wamakhemikhali womuthi olungiselelwe emzimbeni wekati.

Ukukhishwa kwegwebu kusuka emlonyeni wekati kuya ekuphathweni kwezidakamizwa, kokubili ngomlomo kanye nokujova, kungaba yindlela ecasulayo yohlelo lwezinzwa lwekati lokucindezelwa ngenxa yezinyathelo zokwelapha.

Ngokwazisa kukaPapaverine, ukusabela okunjalo kungaba kakhulu (cishe amahlandla ama-5) kubuthakathaka futhi kufushane, ngenxa yokungakhethi okuphansi kwalesi sidakamizwa, umphumela ongabakhona wokuguqula amandla kaPapaverine kanye nempilo esheshayo yengxenye yePapaverine ngokuqhathaniswa neDrotaverinum hydrochloride.

Abanini kwesinye isikhathi bakubiza lokhu ngokuthi “isenzo esithambile” sikaPapaverine uma kuqhathaniswa nesenzo sikaDrotaverin.

Isimo sangaphambi kwekati ngaphambi kokujova i-antispasmodic

Abanikazi abaningi abakubheki ukuthi isikhathi eside i-syndrome yezinhlungu ezihambisana nokuhamba kwezitho eziyize (amathumbu, isigaxa) igcina isimiso sezinzwa sesilwane sisesimweni esihle noma ngabe cishe yonke “imithombo” yomzimba isivele iphelelwe amandla (isigaba esijwayelekile sokukhathazeka kobuhlungu).

Lokhu kuyiqiniso ikakhulukazi ezilwaneni ezinomzimba nezilwane esimweni se-hypoglycemia. Lapho nje isifo sezinhlungu sivele siphelelwe ngamandla ngenxa yomjovo we-antispasmodic, isigaba sesifufula sokwethuka kobuhlungu senzeka: ukuvimbela okubukhali kwazo zonke izinkomba zesistimu yezinzwa, okubandakanya ukwehla kwengcindezi (ukuwa). Isilwane siyaphumula kakhulu (silenga nge-rag), ukusabela kwaso ekunciphiseni okungaphandle kwehla kakhulu, ingcindezi yehla kakhulu, okuthinta ukunikezwa kwegazi kuya ebuchosheni futhi kaningi awukwazi ukukwenza ngaphandle kokuphinda usisuse.

Njengoba kubonakala encazelweni, lokhu akuyona imiphumela emibi ye-antispasmodic, kepha inqubo evamile ye-pathogenetic yokwakhiwa kokwethuka kobuhlungu.

Lokhu kuvame ukubonwa nge-urethral syndrome yamakati (uma ukuphuma komchamo kumiswe ngokuqinile isikhathi esingaphezu kosuku) nangezinhlobo ezithile zokuphazamiseka kwamathumbu, lapho kubukeka imijikelezo ebukhali bese isabalalisa ukubonakala kwamathumbu ngenxa yokwakheka kwegesi.

Ngaleso sizathu-ke ukuzelapha okwenziwe yizilwane esesimweni esibucayi kungamukeleki, ngoba imvamisa umnikazi akakwazi ukubheka yonke imishini esebenza emzimbeni wesiguli esinzima.

Ukuzelapha ngemithi yezilwane esesimweni esibucayi, ikakhulukazi ukusetshenziswa kwe-antispasmodics and analgesics akwamukeleki!

Ukuphendula kwendawo ekuphatheni izidakamizwa

Njengoba kushiwo ngenhla, izixazululo zombili zeDrotaverin nePapaverine zinokusabela kwe-asidi. Ngenxa yalokhu, kuyinto engathandeki kakhulu ukuthi amakati aphathe izidakamizwa ezincanyana ezinama-subcutaneous noma i-intramuscular (interfascial). Umphumela womjovo onjalo uzoba yindawo ebuhlungu yokucasulwa endaweni yomjovo kuze kufike ekwakhiweni kokungena okungapheli.

IPapaverine neDrotaverinum ifiseleka ukungena ngokujulile ngaphakathi kwe-intramuscularly.

Kepha kwenzeka ukuthi ngenxa yezicubu ezincanyana kakhulu futhi ezingakhuli kahle (ngokwesibonelo, kwikithi), umuthi ungene ezingxenyeni ezinamafutha ezinhlobonhlobo, ezingamakhemikhali noma ezinamafutha. Kulokhu, ukusabela kwendawo kwezicubu eziseduze nesixazululo se-acidic kwenzeka. Ubuhlungu obumfishane kungenzeka, obuhambisana ne-lameness, kanye nokuthuthukiswa kokusebenza kokuvuvukala okusebenzayo.

Ukungena okunjalo kuzoba buhlungu kakhulu uma kumboza igatsha lezinzwa noma kusondelene nodonga lwe-vascular, lapho kunama-receptors amaningi ezinhlungu. Ngaphezu kwalokho, uma sibheka ukwehla okungenzeka (kokusebenza kabusha) kokufakwa kanye nomuthi wokuphila wesidakamizwa, kuzocaca ukuthi ukusabela kuDrotaverin kungakhanya futhi kube isikhathi eside kunokuya kuPapaverine.

Uma sikubheka lokho, njengomthetho, imijovo yamakati yenziwa ngokuqondile emilenzeni ye-pelvic, kuba sobala ukuthi kungani isiguli, ngemuva kwezinsuku eziningana zokwelashwa ngemijovo ye-antispasmodic, singamane senqabe ukuhamba ngezinyawo zayo, ukunyakaza ngakunye okubangela izinhlungu.

Le nkinga ingancishiswa ngokusebenzisa ukushisa okomile ukusheshisa ukujikeleza kabusha kokungena ngemuva komjovo.

Yisiphi isidakamizwa ongasithanda?

Ukuze ukhethe futhi uqonde ukuthi yini okufanele uyisebenzise ikati njenge-antispasmodic, kuyadingeka ukubheka wonke amaphuzu nokuhlukahluka okujwayelekile kuzakhiwo zikaDrotaverin noPapaverin, ezikhonjiswe ngenhla.

Engikweluleka ukuthi ugxile kukho:

• Isikhathi esidingekayo sesenzo se-antispasmodic
• Ukuba khona namandla obuhlungu ngaphambi kokusebenzisa i-antispasmodic
• Umphumela ojwayelekile olindelekile kusukela ekusetshenzisweni kwekati le-antispasmodic
• Ukuphendula komuntu ngamunye kwekati ekusebenziseni kwangaphambilini kwama-antispasmodics

Manje cabanga wonke amamaki ngemininingwane eminingi:

Isikhathi esidingekayo sesenzo se-antispasmodic

Uma i-spasm imnene futhi / noma yesikhashana, khona-ke ukujova kwe-papaverine kwanele ukuyihlehlisa.

Uma umphumela wesikhathi eside we-antispasmodic nomthelela omncane ohlelweni lwezinzwa oludingekayo, khona-ke kunengqondo ngokwengeziwe ukukhetha iDrotaverin hydrochloride (No-shpa)

Ngakho-ke, uma udinga ukuqapha okuqhubekayo kwama-mathumbu amancane emathumbu ngenxa yesifo esithathelwanayo noma esihlaselayo (ikakhulukazi kitten), ngincamela ukusebenzisa i-Papaverine, futhi ngenxa yobuhlungu obukhulu be-spastic ngenxa yobuthi, i-idiopathic cystitis noma nge-urolithiasis ne-urethral cat syndrome, nakanjani ngizokhetha iDrotaverine hydrochloride.

Ukuba khona namandla obuhlungu ngaphambi kokusebenzisa i-antispasmodic

Ukuphakama kwezinga lobuhlungu esigulini futhi isikhathi eside lesi sikhathi sobuhlungu, izinyathelo ezengeziwe ezengeziwe engizothatha ukuze ngingasitholi leso sigaba esibuhlungu kakhulu. Ngaphambi kokusebenzisa i-antispasmodic, ngizokhipha imithambo ukuze ngidonse imishanguzo futhi ngilondoloze nengcindezi esigulini, bese ngisebenzisa i-antispasmodic engibona idingeka ngokususelwa kulokhu okungenhla. Uma imiphumela ohlelweni oluphambili lwezinzwa ingathandeki, ukukhetha kwami ​​kuzonikezwa iDrotaverin.

Umphumela ojwayelekile olindelekile kusukela ekusetshenzisweni kwekati le-antispasmodic

Uma ngisebenzisa i-antispasmodic kuphela ukudambisa i-spasm spute esilwaneni esingenazifo ezingamahlalakhona, ngizogxila esikhathini esidingekayo sesenzo se-antispasmodic. Uma ama-antispasmodics asetshenziswa esilwaneni esinenqwaba yezifo ezingamahlalakhona, khona-ke ukusetshenziswa kwama-antispasmodics kuqala ukukhawulelwa yikhono lesiguli lokuphatha umuthi.

Uma sicabangela ukwelashwa kwemishanguzo okukhulunywa ngayo esibindini, ngingathanda ukunquma i-Papaverine yezilwane ezinezinsolo zesifo sokuqina kwesibindi, ukwehla kokudla okungathinta umzimba wesiguli sami kunokuba kube kubi. Esimweni seDrotaverin, ukwehla komthamo wesidakamizwa kungabulala isiguli kakhulu ngenxa yokulondolozwa isikhathi eside emzimbeni futhi, ngenxa yalokho, ubungozi obukhulu bokuqunjelwa.

Ukuphendula komuntu ngamunye kwekati kwizicelo ezedlule ze-antispasmodics

Le ndima, kubonakala kimi, idinga ukuphawulwa okuncane. Kuyacaca ukuthi uma umuzwa wangaphambilini ngalokhu noma ukuthi i-antispasmodic ayiphumelelanga, lapho ngokuzayo kufanele usebenzise esinye isidakamizwa futhi unethemba lokuthi umzimba wesiguli uzosiphendula ngokuya ngokulindelwe okuhle kudokotela nomnikazi.

Kwesinye isikhathi kwenzeka ukuthi ukuguqula nje ukusetwa kwelashwa noma inqubo yokujova kushintsha kakhulu ukusabela kwekati ekuphathweni komuthi. Futhi lokhu, futhi, kufanele kubhekwe lapho uhlela ukwelashwa kweziguli.

Isiphetho

Siyethemba ukuthi izinto zethu esezikhombisile wena mfundi othandekayo, zingaki izinto okufanele zibhekwe lapho ukhetha izidakamizwa zokwelapha isiguli esithile.

Ngakho-ke, uma ungumnikazi wesilwane futhi kubukeka kuwe ukuthi lesi sidakamizwa noma lesi singaba yingozi isilwane sakho, cela udokotela wakho ukuthi akhuthaze ukuqokwa kwakho ngalo muthi othize. Kungenzeka ukuthi ngemuva kwencazelo yezokwelapha, yonke into izovela ingethuseli kangako, kepha ibe kufanele ngokuphelele. Futhi uma okuthile kuhamba ngendlela yakhe, khona-ke ukuxhumana nodokotela kuzosiza ukucacisa izinkinga ezivelile futhi usheshe ushintshe umuthi ngomphumela ongathandeki noma inqubo yokuwusebenzisa.

Qiniseka ukuthi uxoxa nodokotela wakho konke ukwesaba nokukhathazeka kwakho ngokusetshenziswa komuthi othile.

Lokhu kungcono kakhulu kunokulalela udokotela buthule, bese ngokuzimela, ngeseluleko se-Intanethi, shintsha ukwelashwa ngengozi yakho futhi ubeke engcupheni noma uthuke udokotela ongenacala ngokuthile okungeke kwenzeke uma zonke izincomo zilandelwa.

Uma udokotela wezilwane-ke, lapho uchaza lokhu noma lowo muthi, ungalandeli izinganekwane nokwesaba, kepha ulwazi lwe-pharmacology, i-pathophysiology kanye nezifundo zokwelapha.

Sizojabula uma ufuna ukuxoxa ngezinto zethu ngezinhlamvu, imibono ngesihloko esizeni noma emaqenjini ethu!

U-Natya Troshina, Udokotela Wezilwane (i-DVM)

Imithombo yolwazi ngezidakamizwa:

Sithola isifo sohudo - izinhlobo

Ukuxilongwa kwesifo sohudo kungenziwa ngokuzimela ngombala wokugcwala, ukungaguquguquki, ukuba khona kwe-mucus nokuhlanza.

Lapho sesitholile isizathu esidale ukuthi i-kitten's diarrhole, kubalulekile ukwenza ukwelashwa okufanele. Uma ikati inezihlalo ezikhululekile nokuhlanza isikhathi esingaphezu kwesonto, imbangela ingaba yisifo esingamahlalakhona, ngokwesibonelo: i-colitis, ukuvuvukala kwamathumbu, ukutheleleka ngezifo ezithathelwanayo.

Uxolo, okwamanje azikho izikhala zokuvota ezitholakalayo.

Incazelo yesidakamizwa

I-Papaverine ingeqembu le-myotropic antispasmodics. Ngenxa yekhono lokunciphisa ithoni nomsebenzi wezicubu ezisezindongeni eziyize zezitho zangaphakathi, umuthi unomphumela onwebekayo emithanjeni yegazi, okwenza ukuhamba kwegazi kube ngukujwayelekile.

Umuthi ubuye unezinye izakhiwo - i-analgesic, anticonvulsant, yehlise umfutho wegazi. Lokhu kufanele kubhekwe lapho unikeza umuthi ezilwaneni ezifuywayo.

Ukwakheka nefomu lokukhululwa

Ingxenye esebenzayo yesidakamizwa yi-papaverine hydrochloride, enomphumela we-antispasmodic. Le nto iyi-alkaloid ekhiqizwa kusuka ku-opium poppy. Ngaphezu kwalokho, ukwakheka kwalesi sidakamizwa kufaka nezinye izinto. Ukutholakala kwabo kunqunywa uhlobo lokukhululwa.

Abakhiqizi banikeza izinhlobo zemithamo ehlukile ye-papaverine. Efanele kakhulu izilwane ezifuywayo yile:

1. Ukungena.
   Kuketshezi olucacile. Ngokuya ngomenzi, ingapakishwa kuma-ampoules avaliwe noma emabhodleleni epulasitiki. I-1 ml yokwakheka kwemithi iqukethe u-20 mg wento esebenzayo. Ingxenye eyengeziwe ngamanzi ahlanziwe.
2. Amacwecwe.
   IPapaverine elifomu lomthamo inikezwa kwimithamo emi-2 - 10 no-40 mg. Ngaphezu kwalokho, i-stearic acid, isitashi, njll ifakiwe.
3. Ama-suppositories wokuphatha wama-rectal.
   Ama-suppositories mancane ngosayizi futhi abunjwe ngesigaxa. Ziqukethe i-20 mg yento esebenzayo. Izingxenye ezengeziwe - amafutha aqinile, i-stearin, njll. Umuthi ufakwa kumapuleti e-polyvinyl chloride.

Izinkomba kanye ne-contraindication ukuze zisetshenziswe

Umuthi unikezwa amakati kulezi zimo ezilandelayo:

1. Ubuhlungu be-colic kanye nobuhlungu obukhulu obubangelwa yizimo ezahlukahlukene zokugula. Imvamisa ngemuva kokudla ukudla okusindayo, ikati lihlangabezana nobuhlungu futhi lizama ukuheha ukunaka komnikazi ngokucheba. Ithebhulethi yasePapaverine isiza ukukhulula imisipha futhi inciphise spasm.
2. Izifo zohlelo lwe-genitourinary olubangelwa izifo. Ukugcinwa kwe-urinary kungaholela emiphumeleni emibi, ngakho-ke unganqikazi. Ezimweni ezinjalo, odokotela bezilwane batusa imijovo kaPapaverine.
3. I-cystitis yanoma imuphi umsuka, kufaka phakathi kwaqala ngenxa ye-hypothermia yesilwane.
4. I-Pylorospasm (spasm of the sphincter). Le patology ayivamisile ukutholakala emakati. Amakhandlela azosiza ukudambisa izinhlungu.
5. I-Cholecystitis. Ama-spasms avela nge-cholecystitis, izilwane eziqeda amandla. Kuyadingeka ukuthi ususe izinhlungu ngokushesha. Lokhu kwenziwa ngomjovo.

Imvamisa, umuthi ubekwa njengengxenye yokwelapha okuyinkimbinkimbi kanye nezidakamizwa eziqeda imbangela ye-pathology.

Contraindication kokuthatha i-Papaverine:

• ukwehluleka kwesibindi,
• Izinkinga ngezindlala ze-adrenal,
• ukushaqeka noma ukucindezelwa isilwane,
• iminyaka efinyelela ezinyangeni ezi-6
• ukungabekezelelani ngakunye kwezakhi ezakha umuthi.

I-Tachycardia ne-arrhythmia akuyona inkambiso yokuphuza umuthi, kepha ngesikhathi sokwelashwa isilwane kufanele siqashelwe uchwepheshe.

Imiyalo nomthamo

Ukusetshenziswa kwesidakamizwa kuya ngesimo sokukhululwa somuthi.

Ukufakwa imijovo nge-papaverine kwenziwa ngokungenasiphambeko. Le nqubo ayinzima ngisho nakubanikazi bezilwane abangenalwazi. Ukugaya umuthi kufanele kube isipontsho esilahlekayo lapho ibuna. Ukuze wenze lokhu, donsa isikhumba, usihlambe ngobumnene futhi, ngaphandle kokujaha, faka umuthi.

Isikhumba ekushwabeni kwamakati kuyinto eminyene. Kungaba nzima ukuyibhoboza, ngakho-ke odokotela bezilwane bakweluleka ukuthi uthenge imijovo yokujova i-insulin (inenalithi ezacile).

I-Papaverine ingahanjiswa nge-intramuscularly. Kodwa imijovo enjalo izoba buhlungu uma yenziwa ngumuntu ongenalwazi. Ukwakhiwa kwenalithi noma kwezidakamizwa kungangena esizeni esinezihlakala zezinzwa, esidala izinhlungu. Izinkinga ezifanayo zivame ukuhlangana nalabo abaphatha izilwane ekhaya.

Kunzima ukunika amaphilisi, ngoba amakati awawuthandi umuthi. Amakhemikhali wezilwane anikezela ngamadivayisi akhethekile - abethula (othisha bethebhulethi). Ngosizo lwabo, ungafaka umuthi ezimpandeni zolimi.

Uma ungekho ucingo olunjalo, kuzodingeka uguqukele kwindlela ephoqelelwe yokwelashwa. Kuyadingeka ukuvula ngenkani umlomo wekati ubeke iphilisi ezimpandeni zolimi. Ungavumeli isilwane sihambe ngokushesha, ngaphandle kwalokho kuzosikhipha isidakamizwa. Kuyadingeka ukubamba ikhanda lakhe lisesimweni esikhulisiwe isikhashana, kuze kube yilapho ikati lithatha i-sip. Kuvunyelwe ukugaya umuthi bese uxuba nokudla.

Ukuphathwa ngomlomo kwesidakamizwa kunconywa ngesikhathi sokudla. Isisu esingenalutho siyenqaba umuthi.

Ama-suppositories kunzima kakhulu ukuphatha, ngakho odokotela bezilwane banquma le fomu yemithamo ezimweni ezingavamile. Uma udinga ukuthatha i-Papaverine ngendlela yamakhandlela, kufanele ufunde ngokucophelela imiyalo futhi wenze ngokuhambisana nayo. Umuthi ufakwa entuthwaneni.

I-papaverine esetshenziselwa ukwelapha amakati inqunywa udokotela wezilwane. Uchwepheshe uthatha isithombe somtholampilo walesi sifo, isimo sesilwane, njll. Inani lomuthi osetshenzisiwe lincike esindweni sekati. Nge-1 kg yesisindo somzimba wesilwane, kunconywa i-1-2 mg yento esebenzayo.

Isikhathi sokwelashwa sinqunywa nodokotela. Kepha uma isimo sekati singekho ngcono ezinsukwini eziyi-7, ukwelashwa kuyamiswa. Ezimweni ezingavamile kuphela lapho i-papaverine ingabekwa khona isikhathi eside. Ngokuvamile, udokotela wezilwane ukhetha inkambo ehlukile yokwelashwa.

Amakhandlela aqondisayo

Uhlobo lomuthi olusebenza kakhulu nolushesha kunazo zonke ama-supplementories angama-rectal, aphathiselwa isilwane ku-rectum, lapho esincibilika ngokushesha futhi simunca. Amabhola anama-suppositories ayishumi we-20 mg ayatholakala.

Ukuzilawula kwalo muthi, kanye noshintsho olungagunyaziwe umthamo kungaholela emiphumeleni emibi engathandeki kakhulu ngisho nokufa kwesilwane esifuywayo

Nge-colic yamathumbu

Ngemuva kokudla ukudla okusindayo, ubuhlungu bungavela esiswini noma emathunjini, ngenxa yokuthi isilwane asitholi ndawo futhi nge-meow sidonsela ukunaka komnikazi. Kulokhu, ungasiza isilwane ngokunikeza ngomlomo IPapaverine iphilisi, elizophumuza imisipha ebushelelezi yamathumbu futhi inciphise i-spasm.

I-Papaverine ibhekana nobuhlungu kanye ne-spasm yemisipha ebushelelezi emakati, kepha isidakamizwa esiyingozi kakhulu

Ngama-pathologies wesistimu yokugaya ukudla

Izinkinga zokugaya ukudla zingasombululwa Amakhandlela azokunikeza ngokushesha ukukhululeka kwezimpawu ezibuhlungu. Kulokhu, isilwane kuyodingeka sibambe siqine, noma senze isingeniso ngokushesha. Ukuphazamiseka kwephakethe lesisu kudinga ukungenelela okusheshayo, okunganikeza ama-suppositories we-rectal.

Ngezifo ezithathelwanayo zohlelo lwe-genitourinary

Ukutheleleka ngokugcinwa komchamo noma ezinye izifo zohlelo lwezitho zofuzo kuphathwa ngokungenelela kwe-Cardinal, lapho ungangabazi, futhi impilo nokuphila kwesilwane kusengozini. Ezimweni ezinjalo, i-Papaverine isetshenziswa ngemijovo. Umjovo wenziwa lapho ubuna, futhi ukuze usikhiqize, isilwane sithatha “isikhafu sentamo” futhi siyibambe ngokuqinile kuze kube sekupheleni kokulawulwa kwezidakamizwa.

Nge-pylorospasm

I-Sphincter spasm akusona isifo esivame kakhulu emakati, kodwa kwenzeka kwesinye isikhathi. Ngokusobala, kuyadingeka ukususa izimpawu zobuhlungu endaweni, usebenzisa ama-rectal suppositories. Kufanele zifakwe ngokucophelela futhi zibambe isilwane isikhashana ukuze amakhandlela angawa ngaphandle lapho ehamba.

Ngokungeziwe kuma-suppositories, amaphilisi angangezwa ekudleni, ngoba ama-suppositories angavuza ngezakhi ze-sphincter ekhanyayo.

Nge-cholecystitis

I-Cholecystitis iphathwa ngokusetshenziswa okuhlanganisiwe kwemithi. Ukubumba "I-No-shpa", "Papaverine" noma izifanekiselo zayo. Konke lokhu kwethulwa ukuze kusheshe kubuyiselwe izinhlungu ngama-cramps angaqeda isilwane. Ngokuzayo, lapho imvuthuluka inyamalala, ungaqhubeka nokwelashwa okuhlosiwe kwe-urolithiasis ne-cholelithiasis.

Imiyalo yokusebenzisa kanye nomthamo

Ngokuyalela imiyalo yokusebenzisa iPapaverine, umthamo ojwayelekile ngu-1-2 mg ngosuku. Kungcono ukwahlukanisa umthamo ube ngemithamo emibili ukuze ungalethi isilinganiselo somuthi nsuku zonke emzimbeni wesilwane ngasikhathi sinye.

"I-Papaverine" ingasetshenziswa nezinye izinhlobo zama-analgesics

Umthamo uncike kwifomu lokukhululwa nokuqukethwe kwento esebenzayo:

• Isixazululo - 10-50 mg,
• Amakhandlela - 1-2 mg nge-1 kg yesisindo sesilwane. Ungasebenzisa izingcezu ezi-4 ngosuku,
• amaphilisi - ngesilinganiso esingeqi ku-1.5 mg nge-1 kg yesisindo sekati.

IPapaverine kufanele isetshenziselwe amakati ngokulandelayo:

• ikhambi lifakwa kancane futhi ngokucophelela ngaphansi kokubuna,
• Amakhandlela afakwa ku-rectum ngaphandle kwengcindezi eyeqisayo,
• amaphilisi ayachotshozwa futhi engezwa ekudleni.

Ukubuyekezwa komsebenzisi kwenethiwekhi

OKUFANELEKILE: kubuhlungu kakhulu

Mina, njengodokotela, futhi njengesiguli, futhi “njengomama” wesilwane esine-fluffy, esivame ukuhlushwa yi-urolithiasis, we-antispasmodics sikhetha kakhulu i-papaverine. Futhi ngiyamthanda ngalezi zizathu ezilandelayo: + ukulula kokubala umthamo + okusheshayo we-antispasmodic effect + okubaluleke kakhulu ngokuhlanganiswa ne-analgin njenge-ejenti esebenza ngempumelelo ye-antipyretic + kubhekelelwa kalula ngabantu nezilwane (ngokungafani no-shpa) + kuyabiza. Futhi i- "bufus" imnandi kakhulu ngokulula kokuvula ama-ampoules epulasitiki. Akunasidingo sokusika noma sokuphula noma yini, wesabe ukuzisika noma ukuphula i-ampoule. Ngopulasitiki, konke kulula kakhulu. Kukhona incwadi yemiyalezo esebhokisini. Emaphutheni, ngingathanda ukukhipha eyodwa - i-papaverine ingumjovo ogula kakhulu! Futhi uma ifakwe ngokungalungile, khona-ke lapho isisombululo singena ku-nerve fiber, umlenze umane ususwe ebuhlungwini obungabekezeleki isikhathi esithile. Njenganoma iyiphi enye i-antispasmodic, i-papaverine ivuselela imisipha ebushelelezi yezitho zangaphakathi, okusho ukuthi kufanele isetshenziswe ngokuqapha ngezindlela ezahlukahlukene zenhliziyo ukugwema ukuphazamiseka kwesigqi senhliziyo. Okwamanje ngisebenzisa i-papaverine ukwelapha ikati lami kokunye ukuhlaselwa kwe-cystitis, okuhambisana nokugcinwa komchamo. Umthamo we-0,05 ml nge-1 kg yesisindo. Kwethula intramuscularly ethangeni. Ukusebenza kahle kwomuthi kubonakaliswa emandleni okunciphisa imisebe yesinye kanye ne-urethra, ngemuva kwalokho ikati likwazi ukuyochama. Isenzo senzeka ukusuka emizuzwini engama-30 kuye kwali-1. Kusetshenziswa zombili njengengxenye yezifundo eziyinkimbinkimbi zokwelapha, kanye nokunakekelwa okuphuthumayo kwama-spasms ahlukahlukene. Akukho miphumela emibi eye yabonwa kuze kube manje. Ncoma!

Ukungena

Ngidinga kuphi ukufaka umuthi ekati? I-Papaverine ingangenwa intramuscularly and subcutaneously. Ekhaya, kulula ukwenza umjovo ongama-subcutaneous. Kulokhu, lesi silwane sigxilile esiswini, kungakuhle ukuthi omunye umuntu asize ukusigcina. Isikhumba emisebeni sidonswa ngeminwe emibili ukuze isibaya sibe sobude, kuthi ukufakwa inaliti kufaniswe nomgogodla. Kwenqatshelwe ukufaka umuthi nge-angle noma nge-perpendicular emzimbeni.

Isirinji nenaliti kufanele kungaboli. Ngaphambi kokujova umuthi, i-ampoule kufanele ifudunyezwe kancane ezintendeni zezandla zakho, ngakho-ke isilwane sizobekezelela kangcono ubuhlungu obuvela kumjovo. Uma sesiqoqe uketshezi kwisirinji, kufanele unyakaziswe bese kukhiqizwa amabhubuhu womoya.

Umjovo we-intramuscular wenziwa ethangeni lomlenze wangemuva. Imijovo enjalo ibuhlungu kakhulu, mhlawumbe uma inikezwa udokotela wezilwane noma umuntu onolwazi olufanayo. Ngomjovo we-intramuscular, inaliti kufanele ibonakale ebusweni bemisipha.